HNF1A Antibody
Product Specifications
Background
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI Gene ID
6927
Swiss Prot
P20823
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human HNF1A
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Transcription
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=18-937
Calculated Molecular Weight
Observed: 55kDa
Fragment
IgG
Symbol
HNF1A
NCBI Official Name
HNF1 homeobox A
NCBI Organism
Homo sapiens
Other Product Names
TCF1, transcription factor 1, hepatic LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor, HNF1, HNF1A, LFB1, MODY3, Interferon production regulator factor (HNF1), hepatic nuclear factor 1, maturity onset diabetes of the young 3, hepatic, TCF1
Tested Applications
WB, IHC
Physical Properties
Liquid
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