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HNF1A Antibody

Product Specifications

Background

The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.

NCBI Gene ID

6927

Swiss Prot

P20823

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human HNF1A

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Transcription

Purification

Affinity purification

Positive Control

Mouse liver

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 55kDa

Fragment

IgG

Symbol

HNF1A

NCBI Official Name

HNF1 homeobox A

NCBI Organism

Homo sapiens

Other Product Names

TCF1, transcription factor 1, hepatic LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor, HNF1, HNF1A, LFB1, MODY3, Interferon production regulator factor (HNF1), hepatic nuclear factor 1, maturity onset diabetes of the young 3, hepatic, TCF1

Tested Applications

WB, IHC

Physical Properties

Liquid

Frequently Asked Questions

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