IGFBP7 Antibody
Product Specifications
Background
This gene encodes a member of the insulin-like growth factor (IGF) -binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307) .
NCBI Gene ID
3490
Swiss Prot
Q16270
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human IGFBP7
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Positive Control
SW480
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 37kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
IGFBP7
Positive Control 2
K-562
Positive Control 3
293T
Positive Control 4
HepG2
Positive Control 5
U-87MG
Positive Control 6
Mouse spleen
NCBI Official Name
Insulin-like growth factor binding protein 7
NCBI Organism
Homo sapiens
Other Product Names
IGFBP7, FSTL2, IGFBP-7, IGFBP-7v, MAC25, PSF, AGM, TAF, IBP-7, RAMSVPS, IGFBPRP1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
