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GLRA1 Antibody

Product Specifications

Background

The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor, which mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Multiple transcript variants encoding different isoforms have been found.

NCBI Gene ID

2741

Swiss Prot

P23415

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 29-247 of human GLRA1 (NP_000162.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 53kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:1000

Symbol

GLRA1

Positive Control 2

U-251MG

Positive Control 3

Mouse testis

Positive Control 4

Mouse brain

Positive Control 5

Rat testis

NCBI Official Name

Glycine receptor, alpha 1

NCBI Organism

Homo sapiens

Other Product Names

GLRA1, STHE, HKPX1

Tested Applications

WB

Physical Properties

Liquid

Frequently Asked Questions

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