GSN Antibody
Product Specifications
Background
The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF) . Multiple transcript variants encoding several different isoforms have been found for this gene.
NCBI Gene ID
2934
Swiss Prot
P06396
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 543-782 of human GSN (NP_000168.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 109kDa
Fragment
IgG
Symbol
GSN
Positive Control 2
SW480
NCBI Official Name
Gelsolin
NCBI Organism
Homo sapiens
Other Product Names
GSN, DKFZp313L0718, ADF, AGEL
Tested Applications
WB, IF
Physical Properties
Liquid
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