SFRP1 Antibody
Product Specifications
Background
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.
NCBI Gene ID
6422
Swiss Prot
Q8N474
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 30-314 of human SFRP1 (NP_003003.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Neuroscience, Stem Cell
Purification
Affinity purification
Positive Control
NCI-H460
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 35kDa
Fragment
IgG
Symbol
SFRP1
Positive Control 2
293T
Positive Control 3
SKOV3
Positive Control 4
Mouse kidney
NCBI Official Name
Secreted frizzled-related protein 1
NCBI Organism
Homo sapiens
Other Product Names
SFRP1, FRP, FRP1, FrzA, FRP-1, SARP2
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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