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CHRM4 Antibody

Product Specifications

Background

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition.

NCBI Gene ID

1132

Swiss Prot

P08173

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human CHRM4

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

NIH/3T3

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 53kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

CHRM4

NCBI Official Name

Cholinergic receptor muscarinic 4

NCBI Organism

Homo sapiens

Other Product Names

HM4, M4R, muscarinic acetylcholine receptor M4, acetylcholine receptor, muscarinic 4

Tested Applications

WB

Physical Properties

Liquid

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