CDC37 Antibody
Product Specifications
Background
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
NCBI Gene ID
11140
Swiss Prot
Q16543
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human CDC37 (NP_008996.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 50kDa
Fragment
IgG
Symbol
CDC37
Positive Control 2
HeLa
Positive Control 3
HepG2
Positive Control 4
BT474
Positive Control 5
HT-1080
NCBI Official Name
Hsp90 co-chaperone Cdc37
NCBI Organism
Homo sapiens
Other Product Names
Hsp90 co-chaperone Cdc37, Hsp90 chaperone protein kinase-targeting subunit, p50Cdc37, Hsp90 co-chaperone Cdc37, N-terminally processed, CDC37, CDC37A
Tested Applications
WB, IHC, IP
Physical Properties
Liquid
Curated Selection
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