GPT Antibody
Product Specifications
Background
This gene encodes cytosolic alanine aminotransaminase 1 (ALT1) ; also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.
NCBI Gene ID
2875
Swiss Prot
P24298
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human GPT (NP_005300.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 55kDa
Fragment
IgG
Symbol
GPT
Positive Control 2
Mouse lung
Positive Control 3
Mouse intestine
Positive Control 4
Rat liver
Positive Control 5
Rat heart
NCBI Official Name
Glutamic-pyruvate transaminase (alanine aminotransferase)
NCBI Organism
Homo sapiens
Other Product Names
GPT, AAT1, ALT1, GPT1
Tested Applications
WB, IHC
Physical Properties
Liquid
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