IGF2BP3 Antibody
Product Specifications
Background
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
NCBI Gene ID
10643
Swiss Prot
O00425
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human IGF2BP3 (NP_006538.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=18-802
Calculated Molecular Weight
Observed: 72kDa
Fragment
IgG
Symbol
IGF2BP3
Positive Control 2
BxPC-3
Positive Control 3
SGC-7901
Positive Control 4
NIH/3T3
Positive Control 5
293T
Positive Control 6
HepG2
NCBI Official Name
Insulin like growth factor 2 mRNA binding protein 3
NCBI Organism
Homo sapiens
Other Product Names
CT98, IMP-3, IMP3, KOC, KOC1, VICKZ3, insulin-like growth factor 2 mRNA-binding protein 3, IGF-II mRNA-binding protein 3, IGF2 mRNA-binding protein 3, KH domain containing protein overexpressed in cancer, VICKZ family member 3, cancer/testis antigen 98
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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