GNA11 Antibody

The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11) . Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2) . Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.

FBH, FBH2, FHH2, GNA-11, HHC2, HYPOC2, guanine nucleotide-binding protein subunit alpha-11, g alpha-11, guanine nucleotide binding protein (G protein), alpha 11 (Gq class), guanine nucleotide-binding protein G (y) subunit alpha