GNA11 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11) . Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2) . Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.

NCBI Gene ID

2767

Swiss Prot

P29992

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human GNA11

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

BT-474

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 42kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

GNA11

Positive Control 2

SKOV3

Positive Control 3

Mouse brain

Positive Control 4

Mouse kidney

Positive Control 5

Mouse lung

Positive Control 6

Mouse intestine

NCBI Official Name

G protein subunit alpha 11

NCBI Organism

Homo sapiens

Other Product Names

FBH, FBH2, FHH2, GNA-11, HHC2, HYPOC2, guanine nucleotide-binding protein subunit alpha-11, g alpha-11, guanine nucleotide binding protein (G protein), alpha 11 (Gq class), guanine nucleotide-binding protein G (y) subunit alpha