CNTFR Antibody
Product Specifications
Background
This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.
NCBI Gene ID
1271
Swiss Prot
P26992
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 190-340 of human CNTFR (NP_001833.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 41kDa
Fragment
IgG
Applications Notes
WB: 1:400 - 1:2000
Symbol
CNTFR
Positive Control 2
HeLa
Positive Control 3
Mouse brain
Positive Control 4
Mouse heart
Positive Control 5
Rat testis
NCBI Official Name
Ciliary neurotrophic factor receptor
NCBI Organism
Homo sapiens
Other Product Names
CNTFR, ciliary neurotrophic factor receptor, MGC1774, CNTFR alpha, ciliary neurotrophic factor receptor alpha precursor
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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