ABCB8 Antibody
Product Specifications
Background
This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
11194
Swiss Prot
Q9NUT2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 469-718 of human ABCB8 (NP_009119.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 80kDa
Fragment
IgG
Symbol
ABCB8
Positive Control 2
Jurkat
Positive Control 3
HepG2
Positive Control 4
HeLa
Positive Control 5
Mouse heart
Positive Control 6
Mouse skin
NCBI Official Name
ATP-binding cassette, sub-family B (MDR/TAP), member 8
NCBI Organism
Homo sapiens
Other Product Names
ABCB8, EST328128, M-ABC1, MABC1
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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