Occludin Antibody
Product Specifications
Background
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
NCBI Gene ID
100506658
Swiss Prot
Q16625
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 263-522 of human Occludin (NP_002529.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 59kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:2000
Symbol
OCLN
Positive Control 2
Mouse brain
Positive Control 3
Mouse kidney
Positive Control 4
Mouse liver
Positive Control 5
Rat liver
NCBI Official Name
Occludin
NCBI Organism
Homo sapiens
Other Product Names
Occludin, OCLN
Tested Applications
WB
Physical Properties
Liquid
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