NDUFS1 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

4719

Swiss Prot

P28331

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 80-290 of human NDUFS1 (NP_004997.4) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Neuroscience

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 79kDa

Fragment

IgG

Symbol

NDUFS1

Positive Control 2

Raji

Positive Control 3

NCI-H460

Positive Control 4

PC-3

Positive Control 5

293T

Positive Control 6

HepG2

NCBI Official Name

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

NCBI Organism

Homo sapiens

Other Product Names

NDUFS1, PRO1304, OTTHUMP00000206345, NADH-coenzyme Q reductase, NADH dehydrogenase (ubiqui) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase), 75kDa, MGC26839, complex I, mitochondrial respirato, CI-75Kd, CI-75k