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N-WASP Antibody

Product Specifications

Background

This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension.

NCBI Gene ID

8976

Swiss Prot

O00401

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human N-WASP (NP_003932.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 65kDa

Fragment

IgG

Symbol

WASL

Positive Control 2

U-87MG

Positive Control 3

A-549

Positive Control 4

Mouse brain

Positive Control 5

Mouse lung

Positive Control 6

Rat brain

NCBI Official Name

WASP like actin nucleation promoting factor

NCBI Organism

Homo sapiens

Other Product Names

N-WASP, NWASP, WASPB, neural Wiskott-Aldrich syndrome protein, Wiskott-Aldrich syndrome like

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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