YWHAQ Antibody
Product Specifications
Background
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
NCBI Gene ID
10971
Swiss Prot
P27348
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human YWHAQ (NP_006817.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Neuroscience, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
SW480
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 32kDa
Fragment
IgG
Symbol
YWHAQ
Positive Control 2
BT-474
Positive Control 3
HeLa
Positive Control 4
Jurkat
Positive Control 5
Mouse liver
Positive Control 6
Mouse kidney
NCBI Official Name
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
NCBI Organism
Homo sapiens
Other Product Names
YWHAQ, 1C5, HS1, 14-3-3
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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