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DKK1 Antibody

Product Specifications

Background

This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

NCBI Gene ID

22943

Swiss Prot

O94907

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 71-266 of human DKK1 (NP_036374.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Growth Factors, Immunology, Stem Cell

Purification

Affinity purification

Positive Control

Mouse liver

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 29kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:1000

Symbol

DKK1

NCBI Official Name

Dickkopf WNT signaling pathway inhibitor 1

NCBI Organism

Homo sapiens

Other Product Names

DKK1, DKK-1, SK

Tested Applications

WB

Physical Properties

Liquid

Frequently Asked Questions

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