DKK1 Antibody
Product Specifications
Background
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
NCBI Gene ID
22943
Swiss Prot
O94907
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 71-266 of human DKK1 (NP_036374.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Growth Factors, Immunology, Stem Cell
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=18-713
Calculated Molecular Weight
Observed: 29kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:1000
Symbol
DKK1
NCBI Official Name
Dickkopf WNT signaling pathway inhibitor 1
NCBI Organism
Homo sapiens
Other Product Names
DKK1, DKK-1, SK
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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