HMGB1 Antibody, KO Validated
Product Specifications
Background
This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.
NCBI Gene ID
3146
Swiss Prot
P09429
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human HMGB1 (NP_002119.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Apoptosis, Cell Cycle
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 29kDa
Fragment
IgG
Symbol
HMGB1
Positive Control 2
MCF7
Positive Control 3
Jurkat
Positive Control 4
Mouse spleen
Positive Control 5
Mouse lung
Positive Control 6
Mouse kidney
NCBI Official Name
High mobility group box 1
NCBI Organism
Homo sapiens
Other Product Names
HMGB1 Antibody: HMG1, HMG3, SBP-1, HMG1, High mobility group protein B1, High mobility group protein 1, HMG-1
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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