PLK1 Antibody

Product Specifications

Background

The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.

NCBI Gene ID

5347

Swiss Prot

P53350

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 304-603 of human PLK1 (NP_005021.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 65kDa

Fragment

IgG

Symbol

PLK1

Positive Control 2

SW480

Positive Control 3

HT-29

NCBI Official Name

Polo-like kinase 1

NCBI Organism

Homo sapiens

Other Product Names

PLK1, polo-like kinase 1, PLK, STPK13, OTTHUMP00000122462, PLK-1, cell cycle regulated protein kinase, polo (Drosophia) -like kinase, polo like kinase, serine/threonine-protein kinase 13, serine/threonine-protein kinase PLK1