Estrogen Receptor beta Antibody
Product Specifications
Background
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
NCBI Gene ID
2100
Swiss Prot
Q92731
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human Estrogen Receptor beta (NP_001201832.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Obesity, Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
MCF-7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=18-700
Calculated Molecular Weight
Observed: 60kDa
Fragment
IgG
Symbol
ESR2
Positive Control 2
HeLa
Positive Control 3
Mouse ovary
Positive Control 4
Rat ovary
Positive Control 5
Rat kidney
NCBI Official Name
Estrogen receptor 2 (ER beta)
NCBI Organism
Homo sapiens
Other Product Names
ESR2, Erb, ESRB, ESTRB, NR3A2, ER-BETA, ESR-BETA
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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