ENPP2 Antibody
Product Specifications
Background
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
5168
Swiss Prot
Q13822
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 564-863 of human ENPP2 (NP_001035181.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 110-115kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ENPP2
Positive Control 2
A-549
Positive Control 3
Mouse kidney
NCBI Official Name
Ectonucleotide pyrophosphatase/phosphodiesterase 2
NCBI Organism
Homo sapiens
Other Product Names
ENPP2, ectonucleotide pyrophosphatase/phosphodiesterase 2, ATX, ATX-X, AUTOTAXIN, LysoPLD, NPP2, PD-IALPHA, PDNP2, E-NPP 2, autotaxin-t, ectonucleotide pyrophosphatase/phosphodiesterase family member 2, extracellular lysophospholipase D, phosphodiesterase
Tested Applications
WB
Physical Properties
Liquid
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