PSMA4 Antibody

Product Specifications

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

5685

Swiss Prot

P25789

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human PSMA4 (NP_001096137.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Positive Control

293T

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 28kDa

Fragment

IgG

Symbol

PSMA4

Positive Control 2

U-251MG

Positive Control 3

HepG2

Positive Control 4

HeLa

Positive Control 5

Jurkat

Positive Control 6

PC-12

NCBI Official Name

Proteasome (prosome, macropain) subunit, alpha type, 4

NCBI Organism

Homo sapiens

Other Product Names

PSMA4, PSC9, proteasome subun, proteasome component C9, proteasome alpha 4 subunit, proteasome (prosome, macropain) subunit, alpha type, 4, multicatalytic endopeptidase complex subunit C9, MGC24813, MGC12467, MGC111191, macropain subunit C9, HsT17706, HC9