LTA4H Antibody
Product Specifications
Background
The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD) . Several transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
4048
Swiss Prot
P09960
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 312-611 of human LTA4H (NP_000886.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Innate Immunity
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 69kDa
Fragment
IgG
Symbol
LTA4H
Positive Control 2
HepG2
Positive Control 3
PC-3
Positive Control 4
SW620
Positive Control 5
BT-474
Positive Control 6
Ramos
NCBI Official Name
Leukotriene A4 hydrolase
NCBI Organism
Homo sapiens
Other Product Names
LTA4H, LTA4
Tested Applications
WB, IF
Physical Properties
Liquid
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