SIAH1 Antibody
Product Specifications
Background
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
NCBI Gene ID
6477
Swiss Prot
Q8IUQ4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human SIAH1 (NP_001006611.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Neuroscience
Purification
Affinity purification
Positive Control
Mouse kidney
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 31kDa
Fragment
IgG
Symbol
SIAH1
NCBI Official Name
Siah E3 ubiquitin protein ligase 1
NCBI Organism
Homo sapiens
Other Product Names
SIAH1, SIAH1A
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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