Hsc70 Antibody

Product Specifications

Background

This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

3312

Swiss Prot

P11142

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human Hsc70 (NP_006588.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

NIH/3T3

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 70kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

HSPA8

Positive Control 2

Mouse brain

Positive Control 3

Mouse heart

Positive Control 4

Rat brain

Positive Control 5

Rat heart

NCBI Official Name

Heat shock 70kDa protein 8

NCBI Organism

Homo sapiens

Other Product Names

HSPA8, heat shock 70 kDa protein 8, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP, MGC131511, MGC29929, NIP71, LPS-associated protein 1, N-myristoyltransferase inhibitor protein 71, constitutive heat shock protein 70, heat shock 70kD protein 8, heat shock 70kd protein 10, heat shock cognate protein 54, heat shock cognate protein, 71- kDa, lipopolysaccharide-associated protein, uncharacterized bone marrow protein BM034