FLNB Antibody
Product Specifications
Background
This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
NCBI Gene ID
2317
Swiss Prot
O75369
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1686-1785 of human FLNB (NP_001157789.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=18-661
Calculated Molecular Weight
Observed: 298kDa
Fragment
IgG
Symbol
FLNB
Positive Control 2
NIH/3T3
Positive Control 3
A-431
Positive Control 4
Mouse liver
Positive Control 5
Mouse kidney
Positive Control 6
Mouse uterus
NCBI Official Name
Filamin B, beta
NCBI Organism
Homo sapiens
Other Product Names
FLNB, filamin B, beta (actin binding protein 278), ABP-278, AOI, DKFZp686A1668, DKFZp686O033, FH1, FLN1L, LRS1, SCT, TABP, TAP, beta filamin, filamin 1 (actin-binding protein-280) -like, beta (actin-binding protein-278), FLN3
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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