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MTOR Antibody

Product Specifications

Background

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

NCBI Gene ID

2475

Swiss Prot

P42345

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human mTOR (NP_004949.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Autophagy, Cancer, Cell Cycle, Immunology, Obesity, Signal Transduction, Transcription

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 289kDa

Fragment

IgG

Symbol

MTOR

Positive Control 2

K-562

Positive Control 3

U-87MG

NCBI Official Name

Mechanistic target of rapamycin

NCBI Organism

Homo sapiens

Other Product Names

TOR Antibody: FRAP, FRAP1, FRAP2, RAFT1, RAPT1, FRAP, FK506-binding protein 12-rapamycin complex-associated protein 1, mTOR

Tested Applications

WB, IF, IP

Physical Properties

Liquid

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