C-Fos Antibody
Product Specifications
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
NCBI Gene ID
2353
Swiss Prot
P01100
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 90-190 of human c-Fos (NP_005243.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Neuroscience, Signal Transduction, Transcription
Purification
Affinity purification
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Fragment
IgG
Applications Notes
IHC: 1:50 - 1:200
Symbol
FOS
NCBI Official Name
FBJ murine osteosarcoma viral oncogene homolog
NCBI Organism
Homo sapiens
Other Product Names
FOS, p55, AP-1, C-FOS
Tested Applications
IHC
Physical Properties
Liquid
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