MRP4 / ABCC4 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants.

NCBI Gene ID

10257

Swiss Prot

O15439

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 495-705 of human MRP4 / ABCC4 (NP_001098985.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

DU145

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 170kDa

Fragment

IgG

Symbol

ABCC4

Positive Control 2

293T

NCBI Official Name

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

NCBI Organism

Homo sapiens

Other Product Names

BA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4), MRP/cMOAT-related ABC transporter, ATP-binding cassette sub-family C member 4, MRP4, MOATB, MOAT-B, EST170205, ATP-binding cassette, member 4, ABCC4