SELE Antibody

Product Specifications

Background

The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

NCBI Gene ID

6401

Swiss Prot

P16581

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 22-230 of human SELE (NP_000441.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Stem Cell

Purification

Affinity purification

Positive Control

MCF7

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 70kDa

Fragment

IgG

Symbol

SELE

Positive Control 2

HepG2

Positive Control 3

HeLa

Positive Control 4

Raji

Positive Control 5

Mouse liver

NCBI Official Name

Selectin E

NCBI Organism

Homo sapiens

Other Product Names

SELE, selectin E, CD62E, ELAM, ELAM1, ESEL, LECAM2, CD62 antigen-like family member E, E-selectin, ELAM-1, endothelial adhesion molecule 1, endothelial leukocyte adhesion molecule 1, leukocyte endothelial cell adhesion molecule 2, leukocyte-endothelial ce