PMS1 Antibody
Product Specifications
Background
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
NCBI Gene ID
5378
Swiss Prot
P54277
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 405-619 of human PMS1 (NP_000525.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 110kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PMS1
Positive Control 2
MCF7
Positive Control 3
HT-1080
NCBI Official Name
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
NCBI Organism
Homo sapiens
Other Product Names
PMS1, PMS1 postmeiotic segregation increased 1 (S. cerevisiae), PMSL1, hPMS1, HNPCC3, postmeiotic segregation 1, human homolog of yeast mutL, MLH1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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