EPPIN Antibody

Product Specifications

Background

This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility and exhibits antimicrobial activity against E. coli, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

57119

Swiss Prot

O95925

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 22-133 of human EPPIN (NP_065131.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Positive Control

Mouse testis

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 25kDa

Fragment

IgG

Symbol

EPPIN

NCBI Official Name

Epididymal peptidase inhibitor

NCBI Organism

Homo sapiens

Other Product Names

CT71, CT72, SPINLW1, WAP7, WFDC7, dJ461P17.2, eppin, WAP four-disulfide core domain protein 7, cancer/testis antigen 71, cancer/testis antigen 72, epididymal protease inhibitor, epididymis secretory sperm binding protein, protease inhibitor WAP7, serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)