IGF2 Antibody

Product Specifications

Background

This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

3481

Swiss Prot

P01344

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 25-180 of human IGF2 (NP_000603.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Growth Factors, Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 28kDa

Fragment

IgG

Symbol

IGF2

Positive Control 2

SW480

Positive Control 3

Mouse brain

NCBI Official Name

Insulin-like growth factor 2 (somatomedin A)

NCBI Organism

Homo sapiens

Other Product Names

IGF2, somatomedin-A, PP9974, OTTHUMP00000220677, insulin-like growth factor type 2, insulin-like growth factor II, insulin-like growth factor 2 (somatomedin A), IGF-II, FLJ44734, FLJ22066, C11orf43