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HDAC2 Antibody

Product Specifications

Background

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4) . This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

3066

Swiss Prot

Q92769

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 390 to the C-terminus of human HDAC2 (NP_001518.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

K-562

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 60kDa

Fragment

IgG

Symbol

HDAC2

Positive Control 2

NIH/3T3

Positive Control 3

COS-1

Positive Control 4

COS-7

Positive Control 5

HeLa

Positive Control 6

Jurkat

NCBI Official Name

Histone deacetylase 2

NCBI Organism

Homo sapiens

Other Product Names

HDAC2 Antibody: HD2, RPD3, YAF1, Histone deacetylase 2, HD2

Tested Applications

WB, IHC, IF, IP

Physical Properties

Liquid

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