Histone H2AX Antibody
Product Specifications
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
NCBI Gene ID
3014
Swiss Prot
P16104
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human Histone H2AX
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 15kDa
Fragment
IgG
Symbol
H2AFX
Positive Control 2
MCF7
Positive Control 3
HL-60
Positive Control 4
Rat heart
NCBI Official Name
H2A histone family, member X
NCBI Organism
Homo sapiens
Other Product Names
H2AFX, H2A.X, H2A/X, H2AX
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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