PCK1 Antibody
Product Specifications
Background
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
NCBI Gene ID
5105
Swiss Prot
P35558
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 520 to the C-terminus of human PCK1 (NP_002582.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 69kDa
Fragment
IgG
Symbol
PCK1
Positive Control 2
Mouse kidney
NCBI Official Name
Phosphoenolpyruvate carboxykinase 1 (soluble)
NCBI Organism
Homo sapiens
Other Product Names
PCK1, MGC22652, PEPCK-C, PEPCK1, PEPCKC
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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