CLDN7 Antibody
Product Specifications
Background
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.
NCBI Gene ID
1366
Swiss Prot
O95471
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 29-211 of human CLDN7 (NP_001298.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=18-459
Calculated Molecular Weight
Observed: 29kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CLDN7
Positive Control 2
HT-29
Positive Control 3
A-549
Positive Control 4
HO-8910PM
Positive Control 5
Mouse lung
Positive Control 6
Mouse kidney
NCBI Official Name
Claudin 7
NCBI Organism
Homo sapiens
Other Product Names
CLDN7, Claudin-7, Claudin-1, CLDN-7, Hs.84359, CEPTRL2, Claudin 7, CPETRL2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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