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MSX2 Antibody

Product Specifications

Background

This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.

NCBI Gene ID

4488

Swiss Prot

P35548

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-267 of human MSX2 (NP_002440.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction, Transcription

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 29kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

MSX2

Positive Control 2

NIH/3T3

Positive Control 3

C2C12

Positive Control 4

Mouse spinal cord

Positive Control 5

Rat brain

Positive Control 6

Rat uterus

NCBI Official Name

Msh homeobox 2

NCBI Organism

Homo sapiens

Other Product Names

MSX2, FPP, MSH, PFM, CRS2, HOX8, PFM1

Tested Applications

WB

Physical Properties

Liquid

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