TNFSF14 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM) . This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

NCBI Gene ID

8740

Swiss Prot

O43557

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human TNFSF14

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Chemokines & Cytokines, Immunology, Innate Immunity

Purification

Affinity purification

Positive Control

Raji

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 30kDa

Fragment

IgG

Applications Notes

WB: 1:1000 - 1:2000

Symbol

TNFSF14

Positive Control 2

LO2

Positive Control 3

A-549

Positive Control 4

293T

Positive Control 5

THP-1

NCBI Official Name

Tumor necrosis factor (ligand) superfamily, member 14

NCBI Organism

Homo sapiens

Other Product Names

Tumor necrosis factor superfamily member LIGHT, tumor necrosis factor receptor-like 2, tumor necrosis factor ligand superfamily, member 14, ligand for herpesvirus entry mediator, herpesvirus entry mediator A, delta transmembrane LIGHT, TR2, LTg, LIGHT, HVEML, CD258, tumor necrosis factor (ligand) superfamily, TNFSF14, UNQ391/PRO726