MVP Antibody
Product Specifications
Background
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
NCBI Gene ID
9961
Swiss Prot
Q14764
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human MVP (NP_005106.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 100kDa
Fragment
IgG
Symbol
MVP
Positive Control 2
A-549
Positive Control 3
BT-474
Positive Control 4
HeLa
Positive Control 5
HepG2
NCBI Official Name
Major vault protein
NCBI Organism
Homo sapiens
Other Product Names
MVP, Major vault protein, VAULT1, LRP
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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