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MVP Antibody

Product Specifications

Background

This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.

NCBI Gene ID

9961

Swiss Prot

Q14764

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human MVP (NP_005106.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

HT-29

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 100kDa

Fragment

IgG

Symbol

MVP

Positive Control 2

A-549

Positive Control 3

BT-474

Positive Control 4

HeLa

Positive Control 5

HepG2

NCBI Official Name

Major vault protein

NCBI Organism

Homo sapiens

Other Product Names

MVP, Major vault protein, VAULT1, LRP

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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