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SMAD5 Antibody

Product Specifications

Background

The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

4090

Swiss Prot

Q99717

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 186-465 of human SMAD5 (NP_001001420.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

SW480

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 55kDa

Fragment

IgG

Symbol

Smad5

Positive Control 2

BT-474

Positive Control 3

SKOV3

Positive Control 4

MCF7

Positive Control 5

Mouse kidney

Positive Control 6

Rat liver

NCBI Official Name

SMAD family member 5

NCBI Organism

Homo sapiens

Other Product Names

SMAD5, DWFC, JV5-1, MADH5

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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