TNNC1 Antibody
Product Specifications
Background
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.
NCBI Gene ID
7134
Swiss Prot
P63316
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human TNNC1 (NP_003271.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse heart
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 16kDa
Fragment
IgG
Symbol
TNNC1
Positive Control 2
Mouse lung
Positive Control 3
Mouse skeletal muscle
NCBI Official Name
Troponin C type 1 (slow)
NCBI Organism
Homo sapiens
Other Product Names
TNNC1, CMD1Z, Cardiac troponin C, CMH13, Troponin C type 1 (slow), TN-C, TNNC, Troponin C, slow, Troponin C1, slow
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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