MYO7A Antibody
Product Specifications
Background
This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
4647
Swiss Prot
Q13402
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 850-1150 of human MYO7A (NP_000251.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse testis
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 254kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MYO7A
Positive Control 2
Rat testis
NCBI Official Name
Myosin VIIA
NCBI Organism
Homo sapiens
Other Product Names
DFNA11, DFNB2, MYOVIIA, MYU7A, NSRD2, USH1B, unconventional myosin-VIIa, myosin VIIA (Usher syndrome 1B (autosomal recessive, severe) )
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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