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Lamin B1 Antibody, KO Validated

Product Specifications

Background

This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD) . Alternative splicing results in multiple transcript variants.

NCBI Gene ID

4001

Swiss Prot

P20700

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 397-586 of human Lamin B1 (NP_005564.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Validation

Antibody is Knockout validated.

Field of Research

Apoptosis, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 70kDa

Fragment

IgG

Symbol

LMNB1

Positive Control 2

Jurkat

Positive Control 3

HT-29

Positive Control 4

U-251MG

Positive Control 5

A-549

Positive Control 6

Mouse spleen

NCBI Official Name

Lamin B1

NCBI Organism

Homo sapiens

Other Product Names

LMNB1, lamin B1, ADLD, LMN, LMN2, LMNB, MGC111419, OTTHUMP00000159218, lamin-B1

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

Frequently Asked Questions

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