Lamin B1 Antibody, KO Validated
Product Specifications
Background
This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD) . Alternative splicing results in multiple transcript variants.
NCBI Gene ID
4001
Swiss Prot
P20700
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 397-586 of human Lamin B1 (NP_005564.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Apoptosis, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 70kDa
Fragment
IgG
Symbol
LMNB1
Positive Control 2
Jurkat
Positive Control 3
HT-29
Positive Control 4
U-251MG
Positive Control 5
A-549
Positive Control 6
Mouse spleen
NCBI Official Name
Lamin B1
NCBI Organism
Homo sapiens
Other Product Names
LMNB1, lamin B1, ADLD, LMN, LMN2, LMNB, MGC111419, OTTHUMP00000159218, lamin-B1
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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