IL1R2 Antibody
Product Specifications
Background
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.
NCBI Gene ID
7850
Swiss Prot
P27930
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human IL1R2 (NP_775465.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Chemokines & Cytokines, Immunology, Innate Immunity, Stem Cell
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 36kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
IL1R2
Positive Control 2
DU145
Positive Control 3
HeLa
NCBI Official Name
Interleukin 1 receptor, type II
NCBI Organism
Homo sapiens
Other Product Names
IL1R2, type II interleukin-1 receptor, beta, MGC47725, interleukin 1 receptor, type II, IL1RB, CD121b, antigen CDw121b
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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