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RAD9A Antibody

Product Specifications

Background

This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

5883

Swiss Prot

Q99638

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 162-391 of human RAD9A (NP_004575.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle

Purification

Affinity purification

Positive Control

Mouse testis

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 27kDa

Fragment

IgG

Symbol

RAD9A

NCBI Official Name

RAD9 homolog A (S. pombe)

NCBI Organism

Homo sapiens

Other Product Names

RAD9A, RAD9 homolog A (S. pombe), RAD9, RAD9 (S. pombe) homolog, RAD9 homolog, RAD9 homolog (S. pombe), cell cycle checkpoint control protein

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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